WHAT IS CBD​

Cannabidiol—shortened to the acronym CBD—is a naturally occurring chemical found in the Cannabis sativa plant, a type of herbaceous flowering plant. Cannabis is a plant genus that contains many different compounds that can affect the body differently.

Two different cannabis plants are marijuana and hemp. THC (tetrahydrocannabinol) and CBD (cannabidiol) are two of the chemicals found in those plants. Marijuana has higher levels of THC and lower levels of CBD. In comparison, hemp was breed with higher levels of CBD and lower levels of THC.
A prescription form of CBD is used for seizure disorder (epilepsy). CBD is also used for anxiety, pain, a muscle disorder called dystonia, Parkinson disease, Crohn disease, and many other conditions.
Unlike THC, CBD won’t get you high. That’s because CBD does not stimulate cannabinoid receptors in the brain like THC, says Jordan Tishler, MD, President of the Association of Cannabis Specialists. Instead, it changes how those receptors react to THC. For example, researchers have found CBD can weaken THC’s anxiety-causing effects.
 
  • CBD isolate: CBD isolate is the purest form of CBD, containing 99% or more pure CBD. It is free of cannabinoids or terpenes, found in the cannabis plant.
  • Full-spectrum CBD: Full-spectrum CBD contains different cannabis ingredients like cannabinoids and terpenes. It might have trace amounts of THC (usually less than 0.3%).
  • Broad-spectrum CBD: Broad-spectrum CBD is like full-spectrum CBD but without the THC. It still has other elements of the cannabis plant.

WHAT IS THC?

Short for tetrahydrocannabinol, THC is the component in cannabis responsible for the plant’s psychoactive effects. When you feel “high” after using cannabis, that’s because of THC. 

THC is a cannabinoid, a category of chemicals that interact with the body’s endocannabinoid system. By attaching to cannabinoid receptors in the brain, THC activates neurons that influence pleasure, memory, thinking, coordination, and time perception. 

Some research and anecdotal evidence indicate THC may be used to treat a range of medical conditions. And from a recreational standpoint, it can feel good, causing a sensation of euphoria and relaxation in some. 

4 Benefits of THC 

THC is used medicinally to relieve symptoms of certain conditions. But, because cannabis is federally illegal in the United States, research on THC is significantly limited.

“Most of the clinical data we have is anecdotal evidence or evidence from practitioners in states where they allow medical marijuana,” says Amol Soin, MD, the medical director of the Ohio Pain Clinic and member of the Ohio Medical Marijuana board. “Marijuana is a [DEA] schedule one substance, which eliminates the ability to do a lot of clinical trial work.”

Here are some of the emerging benefits, researchers have found so far: 

1. Alleviates pain

Chronic pain relief is the most common reason why people seek medical cannabis. A large 2015 systematic review evaluated cannabis studies in patients with chronic pain and found THC increased the odds for pain improvement by around 40%. 

While clinical trials support the use of cannabis for chronic pain, researchers agree more studies are needed to determine what doses, forms, and combinations of cannabinoids are most therapeutic for chronic pain patients. 

2. Reduces nausea from chemotherapy

Two oral THC-containing drugs — nabilone and dronabinol — have been available for the treatment of chemotherapy-induced nausea and vomiting for more than 30 years

small 2010 study of chemo patients found those who took a THC-containing medicine in combination with standard treatment experienced stronger protection against nausea and vomiting than patients who received the standard treatment alone. 

3. Reduces muscle spasms in paraplegics

Studies suggest THC products can modestly reduce muscle spasms, a common symptom experienced by people with Multiple Sclerosis (MS) and paraplegia. 

In fact, a large 2015 systematic review concluded that THC used in combination with other cannabinoids improved self-reported muscle spasms more than a placebo, although the difference was not statistically significant. 

4. Improves sleep 

Sleep disturbances are typical in people living with health problems like MS and chronic pain. Studies in these groups show THC products can improve short-term sleep problems, reduce sleep disturbances, and decrease the time it takes to fall asleep. However, it’s unclear whether the THC directly affects sleep quality or whether sleep is improved because chronic symptoms were reduced. 

Here’s how long THC can be detected in your system using various testing methods: 

Infrequent Users Frequent Users Chronic Users
Blood test 1 to 2 days 7 days 7 days
Urine test 1 to 3 days 7 to 21 days +30 days
Saliva test 24 hours 30 hours 30 hours
Hair test 90 days 90 days 90 days

what is cbg?

CBG is the “mother” cannabinoid of many other cannabinoids present in the cannabis plant.

Essentially, it’s classified as a minor cannabinoid, but CBG is an extremely important cannabis compound.

In the cannabis plant, CBG can be found in the form of cannabigerolic acid (CBGA), which is the building block of the three main branches of cannabinoids that include cannabidiolic acid (CBDA), tetrahydrocannabinolic acid (THCA), and cannabichromenic acid (CBCA).

CBGA transforms into these three branches of cannabinoid through specific enzymes known as synthases as the cannabis plant matures.

Because most CBGA is synthesized into these other molecular structures, there are very low concentrations of this cannabinoid in mature cannabis plants.

Through a process known as decarboxylation (where heat is applied to the acidic forms of these cannabinoids), CBGA, CBDA, THCA, and CBCA all lose one carbon group.

They are then transformed into the more familiar forms of CBG, CBD, THC, and CBC. 

This is considered the active state of these compounds and where most of their therapeutic benefits are contained.

what is thcA?

Tetrahydrocannabinolic Acid is a precursor to THC, but like all other cannabinoids, it is a derivative of another cannabinoid acid called cannabigerol acid (CBGA). All other cannabinoids trace their parentage to CBGA. THCA and THC may look structurally similar, but they have very significant differences at their molecular level. These minor differences produce diverse effects on the human body. The most notable difference is that THC causes you to get high while THCA does not.

As fresh cannabis buds (flowers) begin to dry, THCA slowly converts into THC. Hence, live cannabis flowers require decarboxylation to activate or produce THC. This is why if you consume cannabis raw, there are no psychoactive effects. Although THCa is easily affected by heat or the sunlight. Decarboxylation is a process that removes the carboxylic acid group of atoms from the THC to deliver the psychoactive THC. 

The processed THC interacts with cannabinoid receptors, where as THCA doesn’t seem to. Although it does not have psychoactive effects, it is still a vital cannabis compound. We cannot have THC without THCA in the first place. The main takeaway here is that in living, or a freshly harvested plant, there is little to no THC, only THCA.

LINK TO RESEARCH

All the documents and researches that we collected above you can read and research yourself. This is not claiming to cure, treat, mitigate, or prevent diseases. You may need to consult with your physician!